Any words that are in black list need to be removed from the main file.

Suppose Blacklist contains these words:
0x000021F0
0x000021F4
0x00002238
0x00002239
0x0000223A
0x00022900

Main file contains these:
0x000021F0
0x000021F1
0x000021F4
0x00002238
0x00002239

The final result should be, in the main file:
0x000021F1


Can anyone help me?
And also if possible, please post the fastest versions incase it's a macro.

The macro below will do it. Make sure you have only the 2 files open and the blacklist file as the focus when executing the macro.

It is important that the blacklist file does not contain blank lines!

The macro property Continue if a Find with Replace not found or Continue if search string not found must be checked for this macro.

InsertMode
ColumnModeOff
HexOff
UnixReOff
Clipboard 9
SelectAll
Copy
EndSelect
Top
NextWindow
Bottom
IfColNumGt 1
InsertLine
EndIf
Top
Paste
ClearClipboard
Clipboard 0
IfColNum 1
"#
"
Else
"
#
"
EndIf
Top
Loop
IfCharIs "#"
DeleteLine
ExitLoop
EndIf
SelectLine
Find MatchCase "^s"
Replace All ""
EndLoop

The macro above works only if there is no line containing a word which exists also as substring at end of another line. For example if there is in the blacklist:

ship
bicycle

and the other list contains

ship
car
starship
truck
bicycle

the result of the macro above would be

car
startruck

The reason is that the macro above does not make sure that entire lines are searched and replaced which is no problem on the data of UltraEditLover. A more general version of the macro above is following macro with 2 small modifications which takes lists like above into account because it replaces always only entire lines.

InsertMode
ColumnModeOff
HexOff
UnixReOff
Clipboard 9
SelectAll
Copy
EndSelect
Top
NextWindow
Bottom
IfColNumGt 1
InsertLine
EndIf
Top
Paste
ClearClipboard
Clipboard 0
IfColNum 1
"#
"
Else
"
#
"
EndIf
Top
Find RegExp "%^([~#^p]^)"
Replace All "!StArT^1"
Loop
IfCharIs "#"
DeleteLine
ExitLoop
EndIf
SelectLine
Find MatchCase "^s"
Replace All ""
EndLoop
Find MatchCase "!StArT"
Replace All ""

THANK you!

UltraEdit THEEE best.

I was going through horrible yet slow and unoptimized Vb6 2 elimination list process .