The methods for closing a file opened in UltraEdit for Windows or UEStudio are:

1. File - Close with default hotkey Ctrl+F4.
   
2. A file can be closed by double clicking with primary mouse button on file's file tab except this feature is disabled at Advanced - Configuration - Application Layout - File Tabs - Miscellaneous by having not checked Double-click tab will close file.
   
3. A middle button click on a file tab can also close a file if this feature is enabled as by default at Advanced - Configuration - Application Layout - File Tabs - Miscellaneous by having checked Middle-button-click will close file.
   
4. A primary mouse button click on X symbol on file tab closes also a file if this feature is enabled at Advanced - Configuration - Application Layout - File Tabs- Operation with Close Tab Button not set to None or On tab bar.
   
5. A primary mouse button click on X symbol on tabs bar with using Not Dockable file tabs of type Single line - drop down file list and On tab bar chosen for Close tab button at Advanced - Configuration - Application Layout - File Tabs- Operation can be also used to close a file.
   
6. A primary mouse button click on X symbol of document window (on main menu bar when document window is maximized) with using Dockable file tabs can be also used to close a file. This symbol does not exist with using Not Dockable file tabs bar.
   
7. A primary mouse button click on X symbol on Open Files title bar can be also used to close active file if this feature is enabled Advanced - Configuration - Application Layout - File Tabs- Miscellaneous with having checked MDI close button closes active file (not file tabs).

The methods for closing UltraEdit or UEStudio on Windows are:

1. File - Exit with default hotkey Alt+F4 exits UltraEdit / UEStudio.
   
2. A primary mouse button click on X symbol in title bar of main window of UltraEdit / UEStudio exits UltraEdit / UEStudio.
   
3. A primary mouse button double click on UltraEdit / UEStudio icon on left side in title bar of main window of UltraEdit / UEStudio exits UltraEdit / UEStudio.
   
4. A primary mouse button click on UltraEdit / UEStudio icon on left side in title bar of main window of UltraEdit / UEStudio and one more primary mouse button click on context menu item Close exits UltraEdit / UEStudio.
   
5. A secondary mouse button click on title bar of main window of UltraEdit / UEStudio and a primary mouse button on context menu item Close exits UltraEdit / UEStudio.